1FU9

SOLUTION STRUCTURE OF THE NINTH ZINC-FINGER DOMAIN OF THE U-SHAPED TRANSCRIPTION FACTOR

1FU9 の概要

• エントリーDOI: 10.2210/pdb1fu9/pdb
• 関連するPDBエントリー: 1FV5
• NMR情報: BMRB: 4939
• 分子名称: U-SHAPED TRANSCRIPTIONAL COFACTOR, ZINC ION (2 entities in total)
• 機能のキーワード: zinc-finger, beta-hairpin + alpha-helix, transcription
• 由来する生物種: Drosophila melanogaster (fruit fly)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 4240.27

構造登録者

Liew, C.K.,Kowalski, K.,Fox, A.H.,Newton, A.,Sharpe, B.K.,Crossley, M.,Mackay, J.P. (登録日: 2000-09-14, 公開日: 2000-10-04, 最終更新日: 2024-05-22)

主引用文献

Liew, C.K.,Kowalski, K.,Fox, A.H.,Newton, A.,Sharpe, B.K.,Crossley, M.,Mackay, J.P.
Solution structures of two CCHC zinc fingers from the FOG family protein U-shaped that mediate protein-protein interactions.
Structure Fold.Des., 8:1157-1166, 2000

PubMed Abstract: Zinc finger domains have traditionally been regarded as sequence-specific DNA binding motifs. However, recent evidence indicates that many zinc fingers mediate specific protein-protein interactions. For instance, several zinc fingers from FOG family proteins have been shown to interact with the N-terminal zinc finger of GATA-1.

PubMed: 11080638
DOI: 10.1016/S0969-2126(00)00527-X

実験手法

SOLUTION NMR