1FT2
CO-CRYSTAL STRUCTURE OF PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A FARNESYL DIPHOSPHATE SUBSTRATE
Summary for 1FT2
| Entry DOI | 10.2210/pdb1ft2/pdb |
| Descriptor | PROTEIN FARNESYLTRANSFERASE, ZINC ION, FARNESYL DIPHOSPHATE, ... (4 entities in total) |
| Functional Keywords | protein farnesyltransferase, farnesyl diphosphate, cancer therapeutics, prenyltransferase, isoprenoid, transferase |
| Biological source | Rattus norvegicus (Norway rat) More |
| Total number of polymer chains | 2 |
| Total formula weight | 83305.74 |
| Authors | Beese, L.S.,Casey, P.J.,Long, S.B. (deposition date: 1998-06-02, release date: 1998-11-04, Last modification date: 2023-08-09) |
| Primary citation | Long, S.B.,Casey, P.J.,Beese, L.S. Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate. Biochemistry, 37:9612-9618, 1998 Cited by PubMed: 9657673DOI: 10.1021/bi980708e PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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