1FT2

CO-CRYSTAL STRUCTURE OF PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A FARNESYL DIPHOSPHATE SUBSTRATE

1FT2 の概要

• エントリーDOI: 10.2210/pdb1ft2/pdb
• 分子名称: PROTEIN FARNESYLTRANSFERASE, ZINC ION, FARNESYL DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: protein farnesyltransferase, farnesyl diphosphate, cancer therapeutics, prenyltransferase, isoprenoid, transferase
• 由来する生物種: Rattus norvegicus (Norway rat); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 83305.74

構造登録者

Beese, L.S.,Casey, P.J.,Long, S.B. (登録日: 1998-06-02, 公開日: 1998-11-04, 最終更新日: 2023-08-09)

• 主引用文献: Long, S.B.,Casey, P.J.,Beese, L.S.; Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate.; Biochemistry, 37:9612-9618, 1998; PubMed: 9657673; DOI: 10.1021/bi980708e

実験手法

X-RAY DIFFRACTION (3.4 Å)