1FRG

CRYSTAL STRUCTURE, SEQUENCE, AND EPITOPE MAPPING OF A PEPTIDE COMPLEX OF AN ANTI-INFLUENZA HA PEPTIDE ANTIBODY FAB 26(SLASH)9: FINE-TUNING ANTIBODY SPECIFICITY

1FRG の概要

• エントリーDOI: 10.2210/pdb1frg/pdb
• 関連するPDBエントリー: 1HIM 1HIN 1IFH
• 分子名称: IGG2A 26/9 FAB (LIGHT CHAIN), IGG2A 26/9 FAB (HEAVY CHAIN), INFLUENZA HEMAGGLUTININ HA1 (STRAIN X47) (RESIDUES 101 - 108), ... (4 entities in total)
• 機能のキーワード: immunoglobulin/virus hemagglutinin, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Mus musculus (mouse); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 48688.33

構造登録者

Churchill, M.E.A.,Wilson, I.A. (登録日: 1994-01-17, 公開日: 1994-05-31, 最終更新日: 2013-09-18)

• 主引用文献: Churchill, M.E.,Stura, E.A.,Pinilla, C.,Appel, J.R.,Houghten, R.A.,Kono, D.H.,Balderas, R.S.,Fieser, G.G.,Schulze-Gahmen, U.,Wilson, I.A.; Crystal structure of a peptide complex of anti-influenza peptide antibody Fab 26/9. Comparison of two different antibodies bound to the same peptide antigen.; J.Mol.Biol., 241:534-556, 1994; PubMed: 7520084; DOI: 10.1006/jmbi.1994.1530

実験手法

X-RAY DIFFRACTION (2.8 Å)