1FQ7

X-RAY STRUCTURE OF INHIBITOR CP-72,647 BOUND TO SACCHAROPEPSIN

1FQ7 の概要

• エントリーDOI: 10.2210/pdb1fq7/pdb
• 関連するPDBエントリー: 1dp5 1fq4 1fq5 1fq6 1fq8 2jxr
• 関連するBIRD辞書のPRD_ID: PRD_000564
• 分子名称: SACCHAROPEPSIN, beta-D-arabino-hexopyranos-2-ulose-(1-2)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-(tert-butoxycarbonyl)-L-phenylalanyl-N-[(2S,3S,5R)-1-cyclohexyl-3-hydroxy-7-methyl-5-(methylcarbamoyl)octan-2-yl]-L-histidinamide, ... (5 entities in total)
• 機能のキーワード: hydrophobic inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Saccharomyces cerevisiae (baker's yeast)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37587.46

構造登録者

Cronin, N.B.,Badasso, M.O.,Tickle, I.J.,Dreyer, T.,Hoover, D.J.,Rosati, R.L.,Humblet, C.C.,Lunney, E.A.,Cooper, J.B. (登録日: 2000-09-04, 公開日: 2000-09-20, 最終更新日: 2020-07-29)

• 主引用文献: Cronin, N.B.,Badasso, M.O.,J Tickle, I.,Dreyer, T.,Hoover, D.J.,Rosati, R.L.,Humblet, C.C.,Lunney, E.A.,Cooper, J.B.; X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.; J.Mol.Biol., 303:745-760, 2000; PubMed: 11061973; DOI: 10.1006/jmbi.2000.4181

実験手法

X-RAY DIFFRACTION (2.8 Å)