1FN1

CRYSTAL STRUCTURE OF 9-AMINO-(N-(2-DIMETHYLAMINO)BUTYL)ACRIDINE-4-CARBOXAMIDE BOUND TO D(CG(5BR)UACG)2

Summary for 1FN1

DescriptorDNA (5'-D(P*GP*(BRO)UP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*(BRO)UP*AP*CP*G)-3'), COBALT (II) ION, ... (5 entities in total)
Functional Keywords9-aminoacridine-4-carboamide, hexanucleotide, intercalation, quadruplex, dna
Total number of polymer chains2
Total molecular weight3913.29
Authors
Adams, A.,Guss, J.M.,Collyer, C.A.,Denny, W.A.,Wakelin, L.P.G. (deposition date: 2000-08-19, release date: 2000-10-30, Last modification date: 2019-07-24)
Primary citation
Adams, A.,Guss, J.M.,Collyer, C.A.,Denny, W.A.,Wakelin, L.P.
A novel form of intercalation involving four DNA duplexes in an acridine-4-carboxamide complex of d(CGTACG)(2).
Nucleic Acids Res., 28:4244-4253, 2000
PubMed: 11058124 (PDB entries with the same primary citation)
DOI: 10.1093/nar/28.21.4244
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.6 Å)
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Structure validation

RfreeClashscoreRSRZ outliers 0.24030MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution