1FKL

ATOMIC STRUCTURE OF FKBP12-RAPAYMYCIN, AN IMMUNOPHILIN-IMMUNOSUPPRESSANT COMPLEX

1FKL の概要

• エントリーDOI: 10.2210/pdb1fkl/pdb
• 分子名称: FK506 BINDING PROTEIN, RAPAMYCIN IMMUNOSUPPRESSANT DRUG (3 entities in total)
• 機能のキーワード: fk506 binding protein, fkbp12, fkbp, cis-trans prolyl-isomerase, rotamase
• 由来する生物種: Bos taurus (cattle)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 12708.60

構造登録者

Wilson, K.P.,Sintchak, M.D.,Thomson, J.A.,Navia, M.A. (登録日: 1995-08-18, 公開日: 1995-12-07, 最終更新日: 2024-02-07)

• 主引用文献: Wilson, K.P.,Yamashita, M.M.,Sintchak, M.D.,Rotstein, S.H.,Murcko, M.A.,Boger, J.,Thomson, J.A.,Fitzgibbon, M.J.,Black, J.R.,Navia, M.A.; Comparative X-ray structures of the major binding protein for the immunosuppressant FK506 (tacrolimus) in unliganded form and in complex with FK506 and rapamycin.; Acta Crystallogr.,Sect.D, 51:511-521, 1995; PubMed: 15299838; DOI: 10.1107/S0907444994014514

実験手法

X-RAY DIFFRACTION (1.7 Å)