1FKJ

ATOMIC STRUCTURE OF FKBP12-FK506, AN IMMUNOPHILIN IMMUNOSUPPRESSANT COMPLEX

Summary for 1FKJ

Entry DOI	10.2210/pdb1fkj/pdb
Descriptor	FK506 BINDING PROTEIN, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN (3 entities in total)
Functional Keywords	fk506 binding protein, fkbp12, cis-trans prolyl-isomerase, rotamase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	12640.53
Authors	Wilson, K.P.,Sintchak, M.D.,Thomson, J.A.,Navia, M.A. (deposition date: 1995-08-18, release date: 1995-12-07, Last modification date: 2024-02-07)
Primary citation	Wilson, K.P.,Yamashita, M.M.,Sintchak, M.D.,Rotstein, S.H.,Murcko, M.A.,Boger, J.,Thomson, J.A.,Fitzgibbon, M.J.,Black, J.R.,Navia, M.A. Comparative X-ray structures of the major binding protein for the immunosuppressant FK506 (tacrolimus) in unliganded form and in complex with FK506 and rapamycin. Acta Crystallogr.,Sect.D, 51:511-521, 1995 Cited by PubMed: 15299838 DOI: 10.1107/S0907444994014514 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation