1FI8
RAT GRANZYME B [N66Q] COMPLEXED TO ECOTIN [81-84 IEPD]
Summary for 1FI8
| Entry DOI | 10.2210/pdb1fi8/pdb |
| Descriptor | NATURAL KILLER CELL PROTEASE 1, ECOTIN, ... (4 entities in total) |
| Functional Keywords | complex (serine protease-inhibitor), protease substrate interactions, beta strand structure, chymotrypsin fold, granzyme b, ecotin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Rattus norvegicus (Norway rat) More |
| Cellular location | Periplasm: P23827 P23827 |
| Total number of polymer chains | 6 |
| Total formula weight | 82799.75 |
| Authors | Waugh, S.M.,Harris, J.L.,Fletterick, R.J.,Craik, C.S. (deposition date: 2000-08-03, release date: 2000-09-13, Last modification date: 2021-11-03) |
| Primary citation | Waugh, S.M.,Harris, J.L.,Fletterick, R.,Craik, C.S. The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity Nat.Struct.Biol., 7:762-765, 2000 Cited by PubMed: 10966646DOI: 10.1038/78992 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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