1FHX
Structure of the pleckstrin homology domain from GRP1 in complex with inositol 1,3,4,5-tetrakisphosphate
Summary for 1FHX
Entry DOI | 10.2210/pdb1fhx/pdb |
Related | 1FHW |
Descriptor | GUANINE NUCLEOTIDE EXCHANGE FACTOR AND INTEGRIN BINDING PROTEIN HOMOLOG GRP1, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | pleckstrin, 3-phosphoinositides, inositol tetrakisphosphate signal transduction protein, guanine nucleotide exchange factor, signaling protein |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 2 |
Total formula weight | 31912.46 |
Authors | Ferguson, K.M.,Kavran, J.M.,Sankaran, V.G.,Fournier, E.,Isakoff, S.J.,Skolnik, E.Y.,Lemmon, M.A. (deposition date: 2000-08-02, release date: 2000-08-23, Last modification date: 2024-10-09) |
Primary citation | Ferguson, K.M.,Kavran, J.M.,Sankaran, V.G.,Fournier, E.,Isakoff, S.J.,Skolnik, E.Y.,Lemmon, M.A. Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains Mol.Cell, 6:373-384, 2000 Cited by PubMed: 10983984DOI: 10.1016/S1097-2765(00)00037-X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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