1FGP

MEMBRANE PENETRATION DOMAIN OF THE MINOR COAT PROTEIN G3P OF PHAGE FD, NMR, 15 STRUCTURES

Summary for 1FGP

• Entry DOI: 10.2210/pdb1fgp/pdb
• Descriptor: FD GENE 3 PROTEIN (1 entity in total)
• Functional Keywords: phage coat protein, sh3 domain, ph domain, pdz domain, fd phage, filamentous pahge, phage infection, ptb domain, viral protein
• Biological source: Enterobacteria phage fd
• Cellular location: Virion (Potential): P03661
• Total number of polymer chains: 1
• Total formula weight: 7711.48

Authors

Holliger, P.,Riechmann, L. (deposition date: 1996-12-10, release date: 1997-06-16, Last modification date: 2024-10-16)

Primary citation

Holliger, P.,Riechmann, L.
A conserved infection pathway for filamentous bacteriophages is suggested by the structure of the membrane penetration domain of the minor coat protein g3p from phage fd.
Structure, 5:265-275, 1997

PubMed Abstract: . Gene 3 protein (g3p), a minor coat protein from bacteriophage fd mediates infection of Escherichia coli bearing an F-pilus. Its N-terminal domain (g3p-D1) is essential for infection and mediates penetration of the phage into the host cytoplasm presumbly through interaction with the Tol complex in the E. coli membranes. Structural knowledge of g3p-D1 is both important for a molecular understanding of phage infection and of biotechnological relevance, as g3p-D1 represents the primary fusion partner in phage display technology.

PubMed: 9032075
DOI: 10.1016/S0969-2126(97)00184-6

Experimental method

SOLUTION NMR