1FFL
CRYSTAL STRUCTURE OF THE APO-THYMIDYLATE SYNTHASE R166Q MUTANT
Summary for 1FFL
| Entry DOI | 10.2210/pdb1ffl/pdb |
| Descriptor | THYMIDYLATE SYNTHASE (2 entities in total) |
| Functional Keywords | transferase, methyltransferase |
| Biological source | Escherichia coli |
| Cellular location | Cytoplasm : P0A884 |
| Total number of polymer chains | 1 |
| Total formula weight | 30530.60 |
| Authors | Sotelo-Mundo, R.R.,Changchien, L.,Maley, F.,Montfort, W.R. (deposition date: 2000-07-25, release date: 2000-07-28, Last modification date: 2024-04-03) |
| Primary citation | Sotelo-Mundo, R.R.,Changchien, L.,Maley, F.,Montfort, W.R. Crystal structures of thymidylate synthase mutant R166Q: Structural basis for the nearly complete loss of catalytic activity. J.Biochem.Mol.Toxicol., 20:88-92, 2006 Cited by PubMed: 16615077DOI: 10.1002/jbt.20122 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.94 Å) |
Structure validation
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