1FE2

CRYSTAL STRUCTURE OF DIHOMO-GAMMA-LINOLEIC ACID BOUND IN THE CYCLOOXYGENASE CHANNEL OF PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1.

1FE2 の概要

• エントリーDOI: 10.2210/pdb1fe2/pdb
• 関連するPDBエントリー: 1DDX 1DIY 1PRH
• 分子名称: PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: membrane protein, fatty acid, dihomo-gamma-linoleic acid, oxidoreductase, peroxidase, dioxygenase
• 由来する生物種: Ovis aries (sheep)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 69727.60

構造登録者

Thuresson, E.D.,Malkowski, M.G.,Lakkides, K.M.,Smith, W.L.,Garavito, R.M. (登録日: 2000-07-20, 公開日: 2001-05-02, 最終更新日: 2020-07-29)

• 主引用文献: Thuresson, E.D.,Malkowski, M.G.,Lakkides, K.M.,Rieke, C.J.,Mulichak, A.M.,Ginell, S.L.,Garavito, R.M.,Smith, W.L.; Mutational and X-ray crystallographic analysis of the interaction of dihomo-gamma -linolenic acid with prostaglandin endoperoxide H synthases.; J.Biol.Chem., 276:10358-10365, 2001; PubMed: 11121413; DOI: 10.1074/jbc.M009378200

実験手法

X-RAY DIFFRACTION (3 Å)