1FCC

CRYSTAL STRUCTURE OF THE C2 FRAGMENT OF STREPTOCOCCAL PROTEIN G IN COMPLEX WITH THE FC DOMAIN OF HUMAN IGG

Summary for 1FCC

Entry DOI	10.2210/pdb1fcc/pdb
Descriptor	IGG1 MO61 FC, STREPTOCOCCAL PROTEIN G (C2 FRAGMENT) (2 entities in total)
Functional Keywords	complex (antibody-antigen), complex (antibody-antigen) complex, complex (antibody/antigen)
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	59354.64
Authors	Sauer-Eriksson, A.E.,Kleywegt, G.J.,Uhlen, M.,Jones, T.A. (deposition date: 1995-01-17, release date: 1995-04-20, Last modification date: 2024-10-16)
Primary citation	Sauer-Eriksson, A.E.,Kleywegt, G.J.,Uhlen, M.,Jones, T.A. Crystal structure of the C2 fragment of streptococcal protein G in complex with the Fc domain of human IgG. Structure, 3:265-278, 1995 Cited by PubMed Abstract: Streptococcal protein G comprises two or three domains that bind to the constant Fc region of most mammalian immunoglobulin Gs (IgGs). Protein G is functionally related to staphylococcal protein A, with which it shares neither sequence nor structural homology. PubMed: 7788293 DOI: 10.1016/S0969-2126(01)00157-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation