1FB8

STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM DAPP1/PHISH

Summary for 1FB8

Entry DOI	10.2210/pdb1fb8/pdb
Related	1FAO
Descriptor	DUAL ADAPTOR OF PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDES, PHOSPHATE ION (3 entities in total)
Functional Keywords	pleckstrin, 3-phosphoinositides, inositol tetrakisphosphate signal transduction protein, adaptor protein, signaling protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	14994.97
Authors	Ferguson, K.M.,Kavran, J.M.,Sankaran, V.G.,Fournier, E.,Isakoff, S.J.,Skolnik, E.Y.,Lemmon, M.A. (deposition date: 2000-07-14, release date: 2000-07-20, Last modification date: 2011-07-13)
Primary citation	Ferguson, K.M.,Kavran, J.M.,Sankaran, V.G.,Fournier, E.,Isakoff, S.J.,Skolnik, E.Y.,Lemmon, M.A. Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains. Mol.Cell, 6:373-384, 2000 Cited by PubMed: 10983984 DOI: 10.1016/S1097-2765(00)00037-X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation