1F8I
CRYSTAL STRUCTURE OF ISOCITRATE LYASE:NITROPROPIONATE:GLYOXYLATE COMPLEX FROM MYCOBACTERIUM TUBERCULOSIS
Summary for 1F8I
Entry DOI | 10.2210/pdb1f8i/pdb |
Related | 1F8M |
Descriptor | ISOCITRATE LYASE, MAGNESIUM ION, GLYOXYLIC ACID, ... (5 entities in total) |
Functional Keywords | alpha-beta barrel, swapped helices, closed conformation, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, lyase |
Biological source | Mycobacterium tuberculosis H37Rv |
Cellular location | Cytoplasm: P0A5H3 |
Total number of polymer chains | 4 |
Total formula weight | 189623.35 |
Authors | Sharma, V.,Sharma, S.,Hoener zu Bentrup, K.,McKinney, J.D.,Russell, D.G.,Jacobs Jr., W.R.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2000-06-30, release date: 2000-12-30, Last modification date: 2024-02-07) |
Primary citation | Sharma, V.,Sharma, S.,Hoener zu Bentrup, K.,McKinney, J.D.,Russell, D.G.,Jacobs Jr., W.R.,Sacchettini, J.C. Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis. Nat.Struct.Biol., 7:663-668, 2000 Cited by PubMed: 10932251DOI: 10.1038/77964 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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