1F8I
CRYSTAL STRUCTURE OF ISOCITRATE LYASE:NITROPROPIONATE:GLYOXYLATE COMPLEX FROM MYCOBACTERIUM TUBERCULOSIS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | ISOCITRATE LYASE | polymer | 429 | 47189.4 | 4 | UniProt (P0A5H3) Pfam (PF00463) UniProt (by SIFTS) (P9WKK7) | Mycobacterium tuberculosis H37Rv | ICL |
| 2 | E, H, K, N (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | F, I, L, O (A, B, C, D) | GLYOXYLIC ACID | non-polymer | 74.0 | 4 | Chemie (GLV) | |||
| 4 | G, J, M, P (A, B, C, D) | SUCCINIC ACID | non-polymer | 118.1 | 4 | Chemie (SIN) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 1052 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 0 - 428 (UniProt: P0A5H3)
| PDB | External Database | Details |
|---|---|---|
| Ala 1 | - | insertion |
| Ser 191 | Cys 191 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 188757.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 865.7 | |
| All* | Total formula weight | 189623.4 |
