1F2V

CRYSTAL STRUCTURE ANALYSIS OF PRECORRIN-8X METHYLMUTASE OF AEROBIC VITAMIN B12 SYNTHESIS

Summary for 1F2V

Entry DOI	10.2210/pdb1f2v/pdb
Descriptor	PRECORRIN-8X METHYLMUTASE (2 entities in total)
Functional Keywords	alpha-beta wind, doubly wound sheet, isomerase
Biological source	Pseudomonas denitrificans
Total number of polymer chains	1
Total formula weight	23217.51
Authors	Shipman, L.W.,Li, D.,Roessner, C.A.,Scott, A.I.,Sacchettini, J.C. (deposition date: 2000-05-29, release date: 2001-07-18, Last modification date: 2024-02-07)
Primary citation	Shipman, L.W.,Li, D.,Roessner, C.A.,Scott, A.I.,Sacchettini, J.C. Crystal structure of precorrin-8x methyl mutase. Structure, 9:587-596, 2001 Cited by PubMed Abstract: The crystal structure of precorrin-8x methyl mutase (CobH), an enzyme of the aerobic pathway to vitamin B12, provides evidence that the mechanism for methyl migration can plausibly be regarded as an allowed [1,5]-sigmatropic shift of a methyl group from C-11 to C-12 at the C ring of precorrin-8x to afford hydrogenobyrinic acid. PubMed: 11470433 DOI: 10.1016/S0969-2126(01)00618-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation