1EZS
CRYSTAL STRUCTURE OF ECOTIN MUTANT M84R, W67A, G68A, Y69A, D70A BOUND TO RAT ANIONIC TRYPSIN II
Summary for 1EZS
Entry DOI | 10.2210/pdb1ezs/pdb |
Related | 1azz 1ecy 1ecz 1ezu 1slu 1slv 1slw 1slx |
Descriptor | ECOTIN, TRYPSIN II, ANIONIC, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | protein-protein interactions, macromolecular complex, protease inhibitor, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Escherichia coli More |
Cellular location | Periplasm: P23827 Secreted, extracellular space: P00763 |
Total number of polymer chains | 4 |
Total formula weight | 79528.42 |
Authors | Gillmor, S.A.,Takeuchi, T.,Yang, S.Q.,Craik, C.S.,Fletterick, R.J. (deposition date: 2000-05-11, release date: 2000-06-23, Last modification date: 2021-11-03) |
Primary citation | Gillmor, S.A.,Takeuchi, T.,Yang, S.Q.,Craik, C.S.,Fletterick, R.J. Compromise and accommodation in ecotin, a dimeric macromolecular inhibitor of serine proteases. J.Mol.Biol., 299:993-1003, 2000 Cited by PubMed: 10843853DOI: 10.1006/jmbi.2000.3812 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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