1EZJ

CRYSTAL STRUCTURE OF THE MULTIMERIZATION DOMAIN OF THE PHOSPHOPROTEIN FROM SENDAI VIRUS

1EZJ の概要

• エントリーDOI: 10.2210/pdb1ezj/pdb
• 分子名称: NUCLEOCAPSID PHOSPHOPROTEIN, ETHYL MERCURY ION, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: four stranded coiled coil, viral polymerase, sendai virus, tetramer, viral protein, transferase
• 由来する生物種: Sendai virus (strain Harris)
• 細胞内の位置: Host cytoplasm: P04859
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13385.54

構造登録者

Tarbouriech, N.,Curran, J.,Ruigrok, R.W.H.,Burmeister, W.P. (登録日: 2000-05-11, 公開日: 2000-09-20, 最終更新日: 2024-02-07)

主引用文献

Tarbouriech, N.,Curran, J.,Ruigrok, R.W.,Burmeister, W.P.
Tetrameric coiled coil domain of Sendai virus phosphoprotein.
Nat.Struct.Biol., 7:777-781, 2000

PubMed Abstract: The high resolution X-ray structure of the Sendai virus oligomerization domain reveals a homotetrameric coiled coil structure with many details that are different from classic coiled coils with canonical hydrophobic heptad repeats. Alternatives to the classic knobs-into-holes packing lead to differences in supercoil pitch and diameter that allow water molecules inside the core. This open and more hydrophilic structure does not seem to be destabilized by mutations that would be expected to disrupt classic coiled coils.

PubMed: 10966649
DOI: 10.1038/79013

実験手法

X-RAY DIFFRACTION (1.9 Å)