1EKB

THE SERINE PROTEASE DOMAIN OF ENTEROPEPTIDASE BOUND TO INHIBITOR VAL-ASP-ASP-ASP-ASP-LYS-CHLOROMETHANE

Summary for 1EKB

Entry DOI	10.2210/pdb1ekb/pdb
Descriptor	ENTEROPEPTIDASE, VAL-ASP-ASP-ASP-ASP-LYK PEPTIDE, ZINC ION, ... (5 entities in total)
Functional Keywords	enteropeptidase, trypsinogen activation, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Bos taurus (cattle) More
Cellular location	Membrane; Single-pass type II membrane protein (Probable): P98072 P98072
Total number of polymer chains	3
Total formula weight	28574.47
Authors	Fuetterer, K.,Lu, D.,Sadler, J.E.,Waksman, G. (deposition date: 1999-05-02, release date: 1999-10-14, Last modification date: 2023-08-02)
Primary citation	Lu, D.,Futterer, K.,Korolev, S.,Zheng, X.,Tan, K.,Waksman, G.,Sadler, J.E. Crystal structure of enteropeptidase light chain complexed with an analog of the trypsinogen activation peptide. J.Mol.Biol., 292:361-373, 1999 Cited by PubMed: 10493881 DOI: 10.1006/jmbi.1999.3089 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation