1EJ6
Reovirus core
Summary for 1EJ6
| Entry DOI | 10.2210/pdb1ej6/pdb |
| Descriptor | LAMBDA2, LAMBDA1, SIGMA2, ... (4 entities in total) |
| Functional Keywords | virus, icosahedral, non-equivalence, dsrna virus, methylase, methyltransferase, guanylyltransferase, zinc finger, icosahedral virus |
| Biological source | Reovirus sp. More |
| Cellular location | Virion : P11079 P15024 P03525 |
| Total number of polymer chains | 5 |
| Total formula weight | 522491.32 |
| Authors | Reinisch, K.M.,Nibert, M.L.,Harrison, S.C. (deposition date: 2000-02-29, release date: 2000-07-12, Last modification date: 2024-02-07) |
| Primary citation | Reinisch, K.M.,Nibert, M.L.,Harrison, S.C. Structure of the reovirus core at 3.6 A resolution. Nature, 404:960-967, 2000 Cited by PubMed Abstract: The reovirus core is an assembly with a relative molecular mass of 52 million that synthesizes, modifies and exports viral messenger RNA. Analysis of its structure by X-ray crystallography shows that there are alternative, specific and completely non-equivalent contacts made by several surfaces of two of its proteins; that the RNA capping and export apparatus is a hollow cylinder, which probably sequesters its substrate to ensure completion of the capping reactions; that the genomic double-stranded RNA is coiled into concentric layers within the particle; and that there is a protein shell that appears to be common to all groups of double-stranded RNA viruses. PubMed: 10801118DOI: 10.1038/35010041 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.6 Å) |
Structure validation
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