1EGC

STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE COMPLEXED WITH OCTANOYL-COA

Summary for 1EGC

Entry DOI	10.2210/pdb1egc/pdb
Descriptor	MEDIUM CHAIN ACYL-COA DEHYDROGENASE, OCTANOYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
Functional Keywords	acyl-coa dehydrogenase, flavoprotein, electron transfer
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion matrix: P11310
Total number of polymer chains	4
Total formula weight	181324.17
Authors	Lee, H.J.,Wang, M.,Paschke, R.,Nandy, A.,Ghisla, S.,Kim, J.P. (deposition date: 1996-04-11, release date: 1997-11-12, Last modification date: 2024-02-07)
Primary citation	Lee, H.J.,Wang, M.,Paschke, R.,Nandy, A.,Ghisla, S.,Kim, J.J. Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity. Biochemistry, 35:12412-12420, 1996 Cited by PubMed: 8823176 DOI: 10.1021/bi9607867 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation