1EGC

STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE COMPLEXED WITH OCTANOYL-COA

Summary for 1EGC

DescriptorMEDIUM CHAIN ACYL-COA DEHYDROGENASE, OCTANOYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
Functional Keywordsacyl-coa dehydrogenase, flavoprotein, electron transfer
Biological sourceHomo sapiens (human)
Cellular locationMitochondrion matrix P11310
Total number of polymer chains4
Total molecular weight181324.17
Authors
Lee, H.J.,Wang, M.,Paschke, R.,Nandy, A.,Ghisla, S.,Kim, J.P. (deposition date: 1996-04-11, release date: 1997-11-12, Last modification date: 2011-07-13)
Primary citation
Lee, H.J.,Wang, M.,Paschke, R.,Nandy, A.,Ghisla, S.,Kim, J.J.
Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity.
Biochemistry, 35:12412-12420, 1996
PubMed: 8823176 (PDB entries with the same primary citation)
DOI: 10.1021/bi9607867
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers201.3%10.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution