1EGC

STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE COMPLEXED WITH OCTANOYL-COA

1EGC の概要

• エントリーDOI: 10.2210/pdb1egc/pdb
• 分子名称: MEDIUM CHAIN ACYL-COA DEHYDROGENASE, OCTANOYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
• 機能のキーワード: acyl-coa dehydrogenase, flavoprotein, electron transfer
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Mitochondrion matrix: P11310
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 181324.17

構造登録者

Lee, H.J.,Wang, M.,Paschke, R.,Nandy, A.,Ghisla, S.,Kim, J.P. (登録日: 1996-04-11, 公開日: 1997-11-12, 最終更新日: 2024-02-07)

• 主引用文献: Lee, H.J.,Wang, M.,Paschke, R.,Nandy, A.,Ghisla, S.,Kim, J.J.; Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity.; Biochemistry, 35:12412-12420, 1996; PubMed: 8823176; DOI: 10.1021/bi9607867

実験手法

X-RAY DIFFRACTION (2.6 Å)