1EEU
M4L/Y(27D)D/Q89D/T94H mutant of LEN
Summary for 1EEU
Entry DOI | 10.2210/pdb1eeu/pdb |
Related | 1EEQ |
Descriptor | KAPPA-4 IMMUNOGLOBULIN (LIGHT CHAIN), ISOPROPYL ALCOHOL (3 entities in total) |
Functional Keywords | human kappa-4 immunoglobulin light chain, mutant, aspartic acid in beta-sheet, protein stability, immune system |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 25335.97 |
Authors | Pokkuluri, P.R.,Cai, X.,Gu, M.,Stevens, F.J.,Schiffer, M. (deposition date: 2000-02-03, release date: 2001-02-03, Last modification date: 2023-08-09) |
Primary citation | Pokkuluri, P.R.,Gu, M.,Cai, X.,Raffen, R.,Stevens, F.J.,Schiffer, M. Factors contributing to decreased protein stability when aspartic acid residues are in beta-sheet regions. Protein Sci., 11:1687-1694, 2002 Cited by PubMed: 12070321DOI: 10.1110/ps.4920102 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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