1EEL

STRUCTURE OF A COMPLEX BETWEEN THE DNA SEQUENCE DCGCGAATTCGCG AND BIS[PIPERIDINO-ETHYL]-FURAMIDINE

Summary for 1EEL

• Entry DOI: 10.2210/pdb1eel/pdb
• Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', 2,5-BIS-[4-[CYCLOPENTA-1,3-DIEN-5-YLAMINO-1-AMINOMETHYL]-PHEN-1-YL]FURAN (3 entities in total)
• Functional Keywords: minor groove binding ligand, b-dna, bulky side-chains, dna
• Total number of polymer chains: 2
• Total formula weight: 7763.33

Authors

Neidle, S.,Simpson, I.J. (deposition date: 2000-02-01, release date: 2000-02-09, Last modification date: 2024-04-03)

• Primary citation: Mazur, S.,Tanious, F.A.,Ding, D.,Kumar, A.,Boykin, D.W.,Simpson, I.J.,Neidle, S.,Wilson, W.D.; A thermodynamic and structural analysis of DNA minor-groove complex formation.; J.Mol.Biol., 300:321-337, 2000; PubMed: 10873468; DOI: 10.1006/jmbi.2000.3869

Experimental method

X-RAY DIFFRACTION (2.4 Å)