1EEL

STRUCTURE OF A COMPLEX BETWEEN THE DNA SEQUENCE DCGCGAATTCGCG AND BIS[PIPERIDINO-ETHYL]-FURAMIDINE

Summary for 1EEL

Descriptor5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', 2,5-BIS-[4-[CYCLOPENTA-1,3-DIEN-5-YLAMINO-1-AMINOMETHYL]-PHEN-1-YL]FURAN (3 entities in total)
Functional Keywordsminor groove binding ligand, b-dna, bulky side-chains, dna
Total number of polymer chains2
Total molecular weight7763.33
Authors
Neidle, S.,Simpson, I.J. (deposition date: 2000-02-01, release date: 2000-02-09, Last modification date: 2017-10-04)
Primary citation
Mazur, S.,Tanious, F.A.,Ding, D.,Kumar, A.,Boykin, D.W.,Simpson, I.J.,Neidle, S.,Wilson, W.D.
A thermodynamic and structural analysis of DNA minor-groove complex formation.
J.Mol.Biol., 300:321-337, 2000
PubMed: 10873468 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.2000.3869
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4 Å)
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Structure validation

Clashscore21MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1eel
no rotation
Molmil generated image of 1eel
rotated about x axis by 90°
Molmil generated image of 1eel
rotated about y axis by 90°