1EED
X-ray crystallographic analysis of inhibition of endothiapepsin by cyclohexyl renin inhibitors
Summary for 1EED
Entry DOI | 10.2210/pdb1eed/pdb |
Related PRD ID | PRD_000265 |
Descriptor | ENDOTHIAPEPSIN, (2S)-2-[[(3S,4S)-5-cyclohexyl-4-[[(4S,5S)-5-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxidanyl-6-phenyl-hexanoyl]amino]-3-oxidanyl-pentanoyl]amino]-4-methyl-pentanoic acid (3 entities in total) |
Functional Keywords | aspartic proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Cryphonectria parasitica (chestnut blight fungus) |
Total number of polymer chains | 1 |
Total formula weight | 34447.67 |
Authors | Blundell, T.L.,Frazao, C.,Cooper, J.B. (deposition date: 1992-06-15, release date: 1994-01-31, Last modification date: 2017-11-29) |
Primary citation | Cooper, J.,Quail, W.,Frazao, C.,Foundling, S.I.,Blundell, T.L.,Humblet, C.,Lunney, E.A.,Lowther, W.T.,Dunn, B.M. X-ray crystallographic analysis of inhibition of endothiapepsin by cyclohexyl renin inhibitors. Biochemistry, 31:8142-8150, 1992 Cited by PubMed: 1525155DOI: 10.1021/bi00150a005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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