1EAZ

Crystal structure of the phosphoinositol (3,4)-bisphosphate binding PH domain of TAPP1 from human.

1EAZ の概要

• エントリーDOI: 10.2210/pdb1eaz/pdb
• 分子名称: TANDEM PH DOMAIN CONTAINING PROTEIN-1, CITRIC ACID (3 entities in total)
• 機能のキーワード: lipid-binding protein, lipid degradation, ph domain, phosphatidylinositol (3, 4)-bisphosphate, signalling, lipid binding protein
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14432.43

構造登録者

Thomas, C.C.,Dowler, S.,Deak, M.,Alessi, D.R.,Van Aalten, D.M.F. (登録日: 2001-07-17, 公開日: 2002-07-11, 最終更新日: 2023-12-13)

• 主引用文献: Thomas, C.C.,Dowler, S.,Deak, M.,Alessi, D.R.,Van Aalten, D.M.F.; Crystal Structure of the Phosphatidylinositol 3,4-Bisphosphate-Binding Pleckstrin Homology (Ph) Domain of Tandem Ph-Domain-Containing Protein 1 (Tapp1): Molecular Basis of Lipid Specificity; Biochem.J., 358:287-, 2001; PubMed: 11513726; DOI: 10.1042/0264-6021:3580287

実験手法

X-RAY DIFFRACTION (1.4 Å)