1EAN
THE RUNX1 Runt domain at 1.70A resolution: A structural switch and specifically bound chloride ions modulate DNA binding
Summary for 1EAN
Entry DOI | 10.2210/pdb1ean/pdb |
Related | 1CMO 1CO1 1E50 1EAO 1EAQ 1H9D 1HJB 1HJC 1IO4 |
Descriptor | RUNT-RELATED TRANSCRIPTION FACTOR 1, CHLORIDE ION (3 entities in total) |
Functional Keywords | transcription-dna complex, acute myeloid leukemia, aml, runx1, runt domain, chloride binding, transcription factor, ig fold, transcription/dna |
Biological source | MUS MUSCULUS (MOUSE) |
Cellular location | Nucleus : Q03347 |
Total number of polymer chains | 1 |
Total formula weight | 15594.46 |
Authors | Backstrom, S.,Wolf-Watz, M.,Grundstrom, C.,Hard, T.,Grundstrom, T.,Sauer, U.H. (deposition date: 2001-07-13, release date: 2002-09-12, Last modification date: 2023-12-13) |
Primary citation | Backstrom, S.,Wolf-Watz, M.,Grundstrom, C.,Hard, T.,Grundstrom, T.,Sauer, U.H. The Runx1 Runt Domain at 1.25 A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate DNA Binding J.Mol.Biol., 322:259-, 2002 Cited by PubMed: 12217689DOI: 10.1016/S0022-2836(02)00702-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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