1E9N
A second divalent metal ion in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1, and its implications for the catalytic mechanism
Summary for 1E9N
Entry DOI | 10.2210/pdb1e9n/pdb |
Related | 1BIX 1CQG 1CQH |
Descriptor | DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE, LEAD (II) ION (3 entities in total) |
Functional Keywords | dna repair, dna repair endonuclease, base excision repair, abasic endonuclease, ape1, hap1, ref-1, alpha, beta sandwich |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 72041.78 |
Authors | Beernink, P.T.,Segelke, B.W.,Rupp, B. (deposition date: 2000-10-24, release date: 2001-02-16, Last modification date: 2024-05-01) |
Primary citation | Beernink, P.T.,Segelke, B.W.,Hadi, M.Z.,Erzberger, J.P.,Wilson III, D.M.,Rupp, B. Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism J.Mol.Biol., 307:1023-, 2001 Cited by PubMed: 11286553DOI: 10.1006/JMBI.2001.4529 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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