1E6A

Fluoride-inhibited substrate complex of Saccharomyces cerevisiae inorganic pyrophosphatase

Summary for 1E6A

• Entry DOI: 10.2210/pdb1e6a/pdb
• Related: 117E 1HUJ 1HUK 1WGI 1WGJ 1YPP 8PRK
• Descriptor: INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, PYROPHOSPHATE 2-, ... (7 entities in total)
• Functional Keywords: phosphoryl transfer, hydrolysis
• Biological source: SACCHAROMYCES CEREVISIAE
• Total number of polymer chains: 2
• Total formula weight: 65493.10

Authors

Heikinheimo, P.,Tuominen, V.,Ahonen, A.-K.,Teplyakov, A.,Cooperman, B.S.,Baykov, A.A.,Lahti, R.,Goldman, A. (deposition date: 2000-08-09, release date: 2001-03-19, Last modification date: 2024-05-08)

• Primary citation: Heikinheimo, P.,Tuominen, V.,Ahonen, A.K.,Teplyakov, A.,Cooperman, B.S.,Baykov, A.A.,Lahti, R.,Goldman, A.; Toward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphatase.; Proc. Natl. Acad. Sci. U.S.A., 98:3121-3126, 2001; PubMed: 11248042; DOI: 10.1073/pnas.061612498

Experimental method

X-RAY DIFFRACTION (1.9 Å)