Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006796 | biological_process | phosphate-containing compound metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006796 | biological_process | phosphate-containing compound metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE MN A2001 |
| Chain | Residue |
| A | ASP115 |
| A | ASP120 |
| A | ASP152 |
| A | MN2002 |
| A | MN2004 |
| A | HOH2334 |
| A | POP3001 |
| A | F4001 |
| A | NA4740 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN A2002 |
| Chain | Residue |
| A | ASP120 |
| A | MN2001 |
| A | HOH2335 |
| A | HOH2336 |
| A | HOH2337 |
| A | POP3001 |
| A | F4001 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A2003 |
| Chain | Residue |
| A | GLU58 |
| A | HOH2338 |
| A | HOH2339 |
| A | HOH2340 |
| A | POP3001 |
| A | NA4740 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A2004 |
| Chain | Residue |
| A | ASP147 |
| A | ASP152 |
| A | MN2001 |
| A | HOH2341 |
| A | HOH2342 |
| A | POP3001 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE F A4001 |
| Chain | Residue |
| A | ASP115 |
| A | ASP117 |
| A | ASP120 |
| A | MN2001 |
| A | MN2002 |
| A | HOH2336 |
| A | POP3001 |
| A | NA4740 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NA A4740 |
| Chain | Residue |
| A | ASP115 |
| A | ASP117 |
| A | MN2001 |
| A | MN2003 |
| A | HOH2165 |
| A | HOH2339 |
| A | POP3001 |
| A | F4001 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE MN B2005 |
| Chain | Residue |
| B | ASP1115 |
| B | ASP1120 |
| B | ASP1152 |
| B | MN2006 |
| B | MN2008 |
| B | HOH2294 |
| B | POP3002 |
| B | PO43004 |
| B | F4010 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MN B2006 |
| Chain | Residue |
| B | ASP1120 |
| B | MN2005 |
| B | HOH2295 |
| B | HOH2296 |
| B | HOH2297 |
| B | POP3002 |
| B | PO43004 |
| B | F4010 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN B2007 |
| Chain | Residue |
| B | GLU1058 |
| B | HOH2298 |
| B | HOH2299 |
| B | HOH2300 |
| B | POP3002 |
| B | PO43003 |
| B | PO43004 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MN B2008 |
| Chain | Residue |
| B | ASP1147 |
| B | ASP1152 |
| B | MN2005 |
| B | HOH2301 |
| B | HOH2302 |
| B | POP3002 |
| B | PO43003 |
| B | PO43004 |
| site_id | BC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE PO4 B3004 |
| Chain | Residue |
| B | LYS1056 |
| B | GLU1058 |
| B | TYR1093 |
| B | ASP1115 |
| B | ASP1117 |
| B | ASP1120 |
| B | ASP1152 |
| B | MN2005 |
| B | MN2006 |
| B | MN2007 |
| B | MN2008 |
| B | HOH2096 |
| B | HOH2297 |
| B | HOH2301 |
| B | HOH2302 |
| B | POP3002 |
| B | PO43003 |
| B | F4010 |
| site_id | BC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE F B4010 |
| Chain | Residue |
| B | HOH2294 |
| B | HOH2295 |
| B | HOH2297 |
| B | POP3002 |
| B | PO43004 |
| B | ASP1115 |
| B | ASP1117 |
| B | ASP1120 |
| B | MN2005 |
| B | MN2006 |
| site_id | BC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE POP A3001 |
| Chain | Residue |
| A | LYS56 |
| A | GLU58 |
| A | ARG78 |
| A | TYR93 |
| A | ASP115 |
| A | ASP117 |
| A | ASP120 |
| A | ASP147 |
| A | ASP152 |
| A | TYR192 |
| A | LYS193 |
| A | MN2001 |
| A | MN2002 |
| A | MN2003 |
| A | MN2004 |
| A | HOH2145 |
| A | HOH2335 |
| A | HOH2339 |
| A | HOH2340 |
| A | HOH2341 |
| A | F4001 |
| A | NA4740 |
| site_id | BC5 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE POP B3002 |
| Chain | Residue |
| B | LYS1056 |
| B | GLU1058 |
| B | ARG1078 |
| B | TYR1093 |
| B | ASP1115 |
| B | ASP1117 |
| B | ASP1120 |
| B | ASP1147 |
| B | ASP1152 |
| B | TYR1192 |
| B | LYS1193 |
| B | MN2005 |
| B | MN2006 |
| B | MN2007 |
| B | MN2008 |
| B | HOH2096 |
| B | HOH2297 |
| B | HOH2300 |
| B | HOH2301 |
| B | HOH2303 |
| B | PO43003 |
| B | PO43004 |
| B | F4010 |
| site_id | BC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PO4 B3003 |
| Chain | Residue |
| B | LYS1056 |
| B | GLU1058 |
| B | ARG1078 |
| B | ASP1147 |
| B | TYR1192 |
| B | LYS1193 |
| B | MN2007 |
| B | MN2008 |
| B | HOH2300 |
| B | HOH2301 |
| B | HOH2303 |
| B | POP3002 |
| B | PO43004 |
Functional Information from PROSITE/UniProt
| site_id | PS00387 |
| Number of Residues | 7 |
| Details | PPASE Inorganic pyrophosphatase signature. DNDPIDV |
| Chain | Residue | Details |
| A | ASP115-VAL121 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"1322842","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"15665377","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| A | ASP117 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| B | ASP1117 | |
