1DXW
structure of hetero complex of non structural protein (NS) of hepatitis C virus (HCV) and synthetic peptidic compound
Summary for 1DXW
Entry DOI | 10.2210/pdb1dxw/pdb |
Related | 1BT7 |
NMR Information | BMRB: 4617 |
Related PRD ID | PRD_000426 |
Descriptor | SERINE PROTEASE, N-(tert-butoxycarbonyl)-L-alpha-glutamyl-N-[(1R)-1-(carboxycarbonyl)-3,3-difluoropropyl]-L-leucinamide, ZINC ION (3 entities in total) |
Functional Keywords | non structural protein, hepatitis c virus, serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | HEPATITIS C VIRUS (HCV) |
Total number of polymer chains | 1 |
Total formula weight | 20209.44 |
Authors | Barbato, G.,Cicero, D.O.,Cordier, F.,Narjes, F.,Gerlach, B.,Sambucini, S.,Grzesiek, S.,Matassa, V.G.,Defrancesco, R.,Bazzo, R. (deposition date: 2000-01-17, release date: 2001-01-12, Last modification date: 2020-01-15) |
Primary citation | Barbato, G.,Cicero, D.O.,Cordier, F.,Narjes, F.,Gerlach, B.,Sambucini, S.,Grzesiek, S.,Matassa, V.G.,Defrancesco, R.,Bazzo, R. Inhibitor Binding Induces Active Site Stabilisation of the Hcv Ns3 Protein Serine Protease Domain Embo J., 19:1195-, 2000 Cited by PubMed: 10716920DOI: 10.1093/EMBOJ/19.6.1195 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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