1DQT
THE CRYSTAL STRUCTURE OF MURINE CTLA4 (CD152)
Summary for 1DQT
Entry DOI | 10.2210/pdb1dqt/pdb |
Descriptor | CYTOTOXIC T LYMPHOCYTE ASSOCIATED ANTIGEN 4, CHLORIDE ION, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | immunoglobulin variable domain-like beta-sandwich, homodimer, immune system |
Biological source | Mus musculus (house mouse) |
Cellular location | Cell membrane ; Single-pass type I membrane protein : P09793 |
Total number of polymer chains | 4 |
Total formula weight | 51914.06 |
Authors | Ostrov, D.A.,Shi, W.,Schwartz, J.C.,Almo, S.C.,Nathenson, S.G. (deposition date: 2000-01-05, release date: 2000-10-27, Last modification date: 2018-01-31) |
Primary citation | Ostrov, D.A.,Shi, W.,Schwartz, J.C.,Almo, S.C.,Nathenson, S.G. Structure of murine CTLA-4 and its role in modulating T cell responsiveness. Science, 290:816-819, 2000 Cited by PubMed: 11052947DOI: 10.1126/science.290.5492.816 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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