1DOA

Structure of the rho family gtp-binding protein cdc42 in complex with the multifunctional regulator rhogdi

Summary for 1DOA

DescriptorPROTEIN (GTP-BINDING PROTEIN), PROTEIN (GDP-DISSOCIATION INHIBITOR 1), MAGNESIUM ION, ... (6 entities in total)
Functional Keywordsgtp-binding protein, cdc42, rhogdi, cell cycle
Biological sourceHomo sapiens (human)
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Cellular locationCell membrane; Lipid-anchor; Cytoplasmic side (Potential) P60953
Cytoplasm P19803
Total number of polymer chains2
Total molecular weight46654.44
Authors
Hoffman, G.R.,Nassar, N.,Cerione, R.C. (deposition date: 1999-12-20, release date: 2000-02-09, Last modification date: 2011-07-13)
Primary citation
Hoffman, G.R.,Nassar, N.,Cerione, R.A.
Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI.
Cell(Cambridge,Mass.), 100:345-356, 2000
PubMed: 10676816 (PDB entries with the same primary citation)
DOI: 10.1016/S0092-8674(00)80670-4
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers133.4%4.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (1doa.pdb2.gz [195.22 KB])
Coordinate files for Biological unit (1doa.pdb1.gz [66.86 KB])