1DM4

SER195ALA MUTANT OF HUMAN THROMBIN COMPLEXED WITH FIBRINOPEPTIDE A (7-16)

Summary for 1DM4

Entry DOI	10.2210/pdb1dm4/pdb
Descriptor	PROTEIN (ALPHA THROMBIN:LIGHT CHAIN), PROTEIN (MUTANT ALPHA THROMBIN:HEAVY CHAIN), PROTEIN (FIBRINOPEPTIDE), ... (4 entities in total)
Functional Keywords	mutant thrombin, residual catalytic activity, fibrinopeptide a, hydrolase
Biological source	Homo sapiens (human) More
Cellular location	Secreted, extracellular space: P00734 P00734
Total number of polymer chains	3
Total formula weight	34907.90
Authors	Krishnan, R.,Sadler, E.J.,Tulinsky, A. (deposition date: 1999-12-13, release date: 2000-01-19, Last modification date: 2018-03-14)
Primary citation	Krishnan, R.,Sadler, J.E.,Tulinsky, A. Structure of the Ser195Ala mutant of human alpha--thrombin complexed with fibrinopeptide A(7--16): evidence for residual catalytic activity. Acta Crystallogr.,Sect.D, 56:406-410, 2000 Cited by PubMed: 10739913 DOI: 10.1107/S0907444900001487 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation