1DM4
SER195ALA MUTANT OF HUMAN THROMBIN COMPLEXED WITH FIBRINOPEPTIDE A (7-16)
Summary for 1DM4
Entry DOI | 10.2210/pdb1dm4/pdb |
Descriptor | PROTEIN (ALPHA THROMBIN:LIGHT CHAIN), PROTEIN (MUTANT ALPHA THROMBIN:HEAVY CHAIN), PROTEIN (FIBRINOPEPTIDE), ... (4 entities in total) |
Functional Keywords | mutant thrombin, residual catalytic activity, fibrinopeptide a, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 |
Total number of polymer chains | 3 |
Total formula weight | 34907.90 |
Authors | Krishnan, R.,Sadler, E.J.,Tulinsky, A. (deposition date: 1999-12-13, release date: 2000-01-19, Last modification date: 2018-03-14) |
Primary citation | Krishnan, R.,Sadler, J.E.,Tulinsky, A. Structure of the Ser195Ala mutant of human alpha--thrombin complexed with fibrinopeptide A(7--16): evidence for residual catalytic activity. Acta Crystallogr.,Sect.D, 56:406-410, 2000 Cited by PubMed: 10739913DOI: 10.1107/S0907444900001487 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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