1DJ9

CRYSTAL STRUCTURE OF 8-AMINO-7-OXONANOATE SYNTHASE (OR 7-KETO-8AMINIPELARGONATE OR KAPA SYNTHASE) COMPLEXED WITH PLP AND THE PRODUCT 8(S)-AMINO-7-OXONANONOATE (OR KAPA). THE ENZYME OF BIOTIN BIOSYNTHETIC PATHWAY.

Summary for 1DJ9

• Entry DOI: 10.2210/pdb1dj9/pdb
• Related: 1BS0
• Descriptor: 8-AMINO-7-OXONONANOATE SYNTHASE, SULFATE ION, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: 8-amino-7-oxononanoate synthase, biotin, pyridoxal-5'-phosphate, transferase
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 42173.87

Authors

Webster, S.P.,Alexeev, D.,Campopiano, D.J.,Watt, R.M.,Alexeeva, M.,Sawyer, L.,Baxter, R.L. (deposition date: 1999-12-02, release date: 2000-12-06, Last modification date: 2024-02-07)

• Primary citation: Webster, S.P.,Alexeev, D.,Campopiano, D.J.,Watt, R.M.,Alexeeva, M.,Sawyer, L.,Baxter, R.L.; Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies.; Biochemistry, 39:516-528, 2000; PubMed: 10642176; DOI: 10.1021/bi991620j

Experimental method

X-RAY DIFFRACTION (2 Å)