1DIY

CRYSTAL STRUCTURE OF ARACHIDONIC ACID BOUND IN THE CYCLOOXYGENASE ACTIVE SITE OF PGHS-1

1DIY の概要

• エントリーDOI: 10.2210/pdb1diy/pdb
• 関連するPDBエントリー: 1CVU 1DDX 1PGE 1PRH 1PTH
• 分子名称: PROSTAGLANDIN H2 SYNTHASE-1, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: arachidonic acid, membrane protein, peroxidase, dioxygenase, oxidoreductase
• 由来する生物種: Ovis aries (sheep)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 67577.28

構造登録者

Malkowski, M.G.,Ginell, S.L.,Smith, W.L.,Garavito, R.M. (登録日: 1999-11-30, 公開日: 2000-09-22, 最終更新日: 2023-08-09)

• 主引用文献: Malkowski, M.G.,Ginell, S.L.,Smith, W.L.,Garavito, R.M.; The productive conformation of arachidonic acid bound to prostaglandin synthase.; Science, 289:1933-1937, 2000; PubMed: 10988074; DOI: 10.1126/science.289.5486.1933

実験手法

X-RAY DIFFRACTION (3 Å)