1DI8
THE STRUCTURE OF CYCLIN-DEPENDENT KINASE 2 (CDK2) IN COMPLEX WITH 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE
Summary for 1DI8
| Entry DOI | 10.2210/pdb1di8/pdb |
| Related | 1DI9 |
| Descriptor | CYCLIN-DEPENDENT KINASE 2, 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE (3 entities in total) |
| Functional Keywords | serine/threonine protein kinase, cell cycle, atp-binding, transferase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 34273.80 |
| Authors | Shewchuk, L.,Hassell, A.,Kuyper, L.F. (deposition date: 1999-11-29, release date: 2000-11-29, Last modification date: 2024-02-07) |
| Primary citation | Shewchuk, L.,Hassell, A.,Wisely, B.,Rocque, W.,Holmes, W.,Veal, J.,Kuyper, L.F. Binding mode of the 4-anilinoquinazoline class of protein kinase inhibitor: X-ray crystallographic studies of 4-anilinoquinazolines bound to cyclin-dependent kinase 2 and p38 kinase. J.Med.Chem., 43:133-138, 2000 Cited by PubMed: 10633045DOI: 10.1021/jm990401t PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report
