1DHI
LONG-RANGE STRUCTURAL EFFECTS IN A SECOND-SITE REVERTANT OF A MUTANT DIHYDROFOLATE REDUCTASE
Summary for 1DHI
Entry DOI | 10.2210/pdb1dhi/pdb |
Descriptor | DIHYDROFOLATE REDUCTASE, CHLORIDE ION, METHOTREXATE, ... (5 entities in total) |
Functional Keywords | oxidoreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 37004.49 |
Authors | Oatley, S.J.,Villafranca, J.E.,Brown, K.A.,Kraut, J. (deposition date: 1993-10-29, release date: 1994-01-31, Last modification date: 2024-02-07) |
Primary citation | Brown, K.A.,Howell, E.E.,Kraut, J. Long-range structural effects in a second-site revertant of a mutant dihydrofolate reductase. Proc.Natl.Acad.Sci.USA, 90:11753-11756, 1993 Cited by PubMed: 8265622DOI: 10.1073/pnas.90.24.11753 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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