1DHI

LONG-RANGE STRUCTURAL EFFECTS IN A SECOND-SITE REVERTANT OF A MUTANT DIHYDROFOLATE REDUCTASE

Summary for 1DHI

DescriptorDIHYDROFOLATE REDUCTASE, CHLORIDE ION, METHOTREXATE, ... (5 entities in total)
Functional Keywordsoxidoreductase
Biological sourceEscherichia coli
Total number of polymer chains2
Total molecular weight37004.49
Authors
Oatley, S.J.,Villafranca, J.E.,Brown, K.A.,Kraut, J. (deposition date: 1993-10-29, release date: 1994-01-31, Last modification date: 2017-11-29)
Primary citation
Brown, K.A.,Howell, E.E.,Kraut, J.
Long-range structural effects in a second-site revertant of a mutant dihydrofolate reductase.
Proc.Natl.Acad.Sci.USA, 90:11753-11756, 1993
PubMed: 8265622 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.90.24.11753
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers120.3%3.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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