1DE7

INTERACTION OF FACTOR XIII ACTIVATION PEPTIDE WITH ALPHA-THROMBIN: CRYSTAL STRUCTURE OF THE ENZYME-SUBSTRATE COMPLEX

1DE7 の概要

• エントリーDOI: 10.2210/pdb1de7/pdb
• 分子名称: ALPHA-THROMBIN (LIGHT CHAIN), ALPHA-THROMBIN (HEAVY CHAIN), FACTOR XIII ACTIVATION PEPTIDE (28-37), ... (5 entities in total)
• 機能のキーワード: enzyme-substrate complex, alpha-thrombin, factor xiii activation peptide, hydrolase/peptide, blood clotting, hydrolase-hydrolase substrate complex, hydrolase/hydrolase substrate
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted, extracellular space: P00734 P00734
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 70065.01

構造登録者

Sadasivan, C.,Yee, V.C. (登録日: 1999-11-13, 公開日: 2000-12-13, 最終更新日: 2023-08-09)

• 主引用文献: Sadasivan, C.,Yee, V.C.; Interaction of the factor XIII activation peptide with alpha -thrombin. Crystal structure of its enzyme-substrate analog complex.; J.Biol.Chem., 275:36942-36948, 2000; PubMed: 10956659; DOI: 10.1074/jbc.M006076200

実験手法

X-RAY DIFFRACTION (2 Å)