1DBW

CRYSTAL STRUCTURE OF FIXJ-N

Summary for 1DBW

Entry DOI	10.2210/pdb1dbw/pdb
Related	1D5W 1DCK 1DCM
Descriptor	TRANSCRIPTIONAL REGULATORY PROTEIN FIXJ, POLYETHYLENE GLYCOL (N=34) (3 entities in total)
Functional Keywords	doubly wound five-stranded beta/alpha fold, nitrogen fixation regulation, transcription
Biological source	Sinorhizobium meliloti
Cellular location	Cytoplasm : P10958
Total number of polymer chains	2
Total formula weight	29289.85
Authors	Gouet, P.,Fabry, B.,Guillet, V.,Birck, C.,Mourey, L.,Kahn, D.,Samama, J.P. (deposition date: 1999-11-03, release date: 1999-11-26, Last modification date: 2024-02-07)
Primary citation	Gouet, P.,Fabry, B.,Guillet, V.,Birck, C.,Mourey, L.,Kahn, D.,Samama, J.P. Structural transitions in the FixJ receiver domain. Structure Fold.Des., 7:1517-1526, 1999 Cited by PubMed Abstract: Two-component signal transduction pathways are sophisticated phosphorelay cascades widespread in prokaryotes and also found in fungi, molds and plants. FixL/FixJ is a prototypical system responsible for the regulation of nitrogen fixation in the symbiotic bacterium Sinorhizobium meliloti. In microaerobic conditions the membrane-bound kinase FixL uses ATP to transphosphorylate a histidine residue, and the response regulator FixJ transfers the phosphoryl group from the phosphohistidine to one of its own aspartate residues in a Mg(2+)-dependent mechanism. PubMed: 10647182 DOI: 10.1016/S0969-2126(00)88342-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation