1D4T

CRYSTAL STRUCTURE OF THE XLP PROTEIN SAP IN COMPLEX WITH A SLAM PEPTIDE

Summary for 1D4T

• Entry DOI: 10.2210/pdb1d4t/pdb
• Related: 1D1Z 1D4W
• Descriptor: T CELL SIGNAL TRANSDUCTION MOLECULE SAP, SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE (3 entities in total)
• Functional Keywords: sh2 domain, tyrosine kinase, signal transduction, peptide recognition, signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : O60880; Cell membrane ; Single-pass type I membrane protein. Isoform 3: Secreted . Isoform 4: Cell membrane : Q13291
• Total number of polymer chains: 2
• Total formula weight: 12982.91

Authors

Poy, F.,Yaffe, M.B.,Sayos, J.,Saxena, K.,Eck, M.J. (deposition date: 1999-10-06, release date: 1999-10-14, Last modification date: 2024-02-07)

• Primary citation: Poy, F.,Yaffe, M.B.,Sayos, J.,Saxena, K.,Morra, M.,Sumegi, J.,Cantley, L.C.,Terhorst, C.,Eck, M.J.; Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition.; Mol.Cell, 4:555-561, 1999; PubMed: 10549287; DOI: 10.1016/S1097-2765(00)80206-3

Experimental method

X-RAY DIFFRACTION (1.1 Å)