1D3H

HUMAN DIHYDROOROTATE DEHYDROGENASE COMPLEXED WITH ANTIPROLIFERATIVE AGENT A771726

Summary for 1D3H

• Entry DOI: 10.2210/pdb1d3h/pdb
• Related: 1D3G
• Descriptor: DIHYDROOROTATE DEHYDROGENASE, SULFATE ION, ACETATE ION, ... (7 entities in total)
• Functional Keywords: alpha-beta barrel, membrane binding motif, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion inner membrane; Single-pass membrane protein: Q02127
• Total number of polymer chains: 1
• Total formula weight: 40894.29

Authors

Liu, S.,Neidhardt, E.A.,Grossman, T.H.,Ocain, T.,Clardy, J. (deposition date: 1999-09-29, release date: 2000-08-13, Last modification date: 2024-02-07)

• Primary citation: Liu, S.,Neidhardt, E.A.,Grossman, T.H.,Ocain, T.,Clardy, J.; Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents.; Structure Fold.Des., 8:25-33, 2000; PubMed: 10673429; DOI: 10.1016/S0969-2126(00)00077-0

Experimental method

X-RAY DIFFRACTION (1.8 Å)