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1CZI

CHYMOSIN COMPLEX WITH THE INHIBITOR CP-113972

Summary for 1CZI
Entry DOI10.2210/pdb1czi/pdb
Related PRD IDPRD_000344
DescriptorCHYMOSIN, CP-113972 (NORSTATINE-S-METHYL CYSTEINE-IODO-PHENYLALANINE-PROLINE) (3 entities in total)
Functional Keywordsacid proteinase, aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceBos taurus (cattle)
Total number of polymer chains2
Total formula weight36403.39
Authors
Groves, M.R.,Dhanaraj, V.,Pitts, J.E.,Badasso, M.,Hoover, D.,Nugent, P.,Blundell, T.L. (deposition date: 1997-01-15, release date: 1997-04-01, Last modification date: 2023-11-15)
Primary citationGroves, M.R.,Dhanaraj, V.,Badasso, M.,Nugent, P.,Pitts, J.E.,Hoover, D.J.,Blundell, T.L.
A 2.3 A resolution structure of chymosin complexed with a reduced bond inhibitor shows that the active site beta-hairpin flap is rearranged when compared with the native crystal structure.
Protein Eng., 11:833-840, 1998
Cited by
PubMed: 9862200
DOI: 10.1093/protein/11.10.833
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

217705

数据于2024-03-27公开中

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