1CZI

CHYMOSIN COMPLEX WITH THE INHIBITOR CP-113972

1CZI の概要

• エントリーDOI: 10.2210/pdb1czi/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000344
• 分子名称: CHYMOSIN, CP-113972 (NORSTATINE-S-METHYL CYSTEINE-IODO-PHENYLALANINE-PROLINE) (3 entities in total)
• 機能のキーワード: acid proteinase, aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Bos taurus (cattle)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36403.39

構造登録者

Groves, M.R.,Dhanaraj, V.,Pitts, J.E.,Badasso, M.,Hoover, D.,Nugent, P.,Blundell, T.L. (登録日: 1997-01-15, 公開日: 1997-04-01, 最終更新日: 2023-11-15)

• 主引用文献: Groves, M.R.,Dhanaraj, V.,Badasso, M.,Nugent, P.,Pitts, J.E.,Hoover, D.J.,Blundell, T.L.; A 2.3 A resolution structure of chymosin complexed with a reduced bond inhibitor shows that the active site beta-hairpin flap is rearranged when compared with the native crystal structure.; Protein Eng., 11:833-840, 1998; PubMed: 9862200; DOI: 10.1093/protein/11.10.833

実験手法

X-RAY DIFFRACTION (2.3 Å)