1CX3

SOLUTION STRUCTURE OF A COMPLEX BETWEEN D(ATGCAT)2 AND THE ANTITUMOR BISNAPHTHALIMIDE LU-79553

Summary for 1CX3

• Entry DOI: 10.2210/pdb1cx3/pdb
• Descriptor: DNA (5'-D(*AP*TP*GP*CP*AP*T)-3'), N,N'-(3,7-DIAZANONYLENE)-BIS-NAPHTHALIMIDE (2 entities in total)
• Functional Keywords: topoisomerase, anticancer, dna, naphthalimide, intercalation, deoxyribonucleic acid
• Total number of polymer chains: 2
• Total formula weight: 4139.05

Authors

Gallego, J.,Reid, B.R. (deposition date: 1999-08-27, release date: 1999-11-19, Last modification date: 2022-02-16)

• Primary citation: Gallego, J.,Reid, B.R.; Solution structure and dynamics of a complex between DNA and the antitumor bisnaphthalimide LU-79553: intercalated ring flipping on the millisecond time scale.; Biochemistry, 38:15104-15115, 1999; PubMed: 10563793; DOI: 10.1021/bi9915869

Experimental method

SOLUTION NMR