1CX3

SOLUTION STRUCTURE OF A COMPLEX BETWEEN D(ATGCAT)2 AND THE ANTITUMOR BISNAPHTHALIMIDE LU-79553

Summary for 1CX3

DescriptorDNA (5'-D(*AP*TP*GP*CP*AP*T)-3'), N,N'-(3,7-DIAZANONYLENE)-BIS-NAPHTHALIMIDE (2 entities in total)
Functional Keywordstopoisomerase, anticancer, dna, naphthalimide, intercalation, deoxyribonucleic acid
Total number of polymer chains2
Total molecular weight4139.05
Authors
Gallego, J.,Reid, B.R. (deposition date: 1999-08-27, release date: 1999-11-19, Last modification date: 2011-07-13)
Primary citation
Gallego, J.,Reid, B.R.
Solution structure and dynamics of a complex between DNA and the antitumor bisnaphthalimide LU-79553: intercalated ring flipping on the millisecond time scale.
Biochemistry, 38:15104-15115, 1999
PubMed: 10563793 (PDB entries with the same primary citation)
DOI: 10.1021/bi9915869
MImport into Mendeley
Experimental method
SOLUTION NMR
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Structure validation

Clashscore0MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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171588
PDB entries from 2020-11-25