1CWT

HUMAN CDC25B CATALYTIC DOMAIN WITH METHYL MERCURY

Summary for 1CWT

Entry DOI	10.2210/pdb1cwt/pdb
Related	1CWR 1CWS 1QB0
Descriptor	CDC25 B-TYPE TYROSINE PHOSPHATASE, SULFATE ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	hydrolase, cell cycle phosphatase, dual specificity protein phosphatase, cdc25, cdc25b, cell cycle
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytoskeleton, centrosome: P30305
Total number of polymer chains	1
Total formula weight	21475.32
Authors	Watenpaugh, K.D.,Reynolds, R.A. (deposition date: 1999-08-26, release date: 2000-08-30, Last modification date: 2024-02-07)
Primary citation	Reynolds, R.A.,Yem, A.W.,Wolfe, C.L.,Deibel Jr., M.R.,Chidester, C.G.,Watenpaugh, K.D. Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle. J.Mol.Biol., 293:559-568, 1999 Cited by PubMed: 10543950 DOI: 10.1006/jmbi.1999.3168 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation